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DXneb™-Solo Vibration Mesh Nebulizer (MESH)
Product Details
| Product Picture | Features |
|---|---|
 |
• Advanced vibrating sieve hole atomization drug delivery technology
Silent (rarely inhaled when the child cries)
• Design advantages of installed piping to improve suction efficiency
High efficiency (high lung deposition rate, fast, good curative effect)
• No additional air supply required (battery driven)
• Screen vibration produces fog
• uniform particle size
• Small drug residues ( <0.1ml,20ml Medicine)
|
Piezoelectric Mesh Nebulizer
Medical piezoelectric vibrating-mesh nebulizer designed for in-hospital therapy, suitable for spontaneous breathing and assisted ventilation patients, with uniform particles, low drug residue and quiet operation.
01. One key operation
Simple and convenient, it can be atomized with just one tap, and it can be easily used by children.
02. Smooth fog
The proportion of particles below 5 m is high, the atomization rate is moderate, the particles are fine, and the throat is not choked.
03. Skin friendly and no peculiar smell
Available with mask and mouthpiece options, with pediatric and adult masks to suit different departments and patient populations.
04. Dual power supply mode
Built-in battery, long battery life, can use the universal charging interface for charging.
Product advantages
- Advanced vibrating screen hole atomization drug delivery technology,
- Silence (little inhalation of medicine when the child is crying),
- The advantages of the Disibo atomizer in the installation pipeline,
- High efficiency (high lung deposition rate, fast, good curative effect),
- Safety (no aerosol pollution) authority certification and recommend (international article data support, global new crown recommend use)
- Suitable for patients with the whole treatment: invasive/non-invasive/nasal high flow/high frequency ventilation/oxygen side atomization;
- Suitable for various departments, focusing on acute and severe cases;
- Efficient treatment, save patient costs, increase the hospital bed turnover rate;
- Nebulizers designated for use during the new crown outbreak;
- Preferred Carriers for Aerosolized Administration
atomization particle size analysis
Analysis of Reachable Positions of Different Drug Aerosol Particles
| Particle size | Deposition |
| > 10μm | 100% deposited in oropharynx |
| 5-10μm | upper airway and upper airway |
| 2-5μm | lower respiratory tract |
| 1-2μm | alveoli |
| <1μm | Not deposited, exhaled |
Product Positioning
DSB Medical’s piezoelectric vibrating-mesh nebulizer system is engineered for in-hospital treatment — covering ICU, NICU, pediatrics, respiratory and elderly care. It serves spontaneously breathing patients as well as those on assisted ventilation (invasive/non-invasive mechanical ventilation, high-flow nasal cannula, tracheostomy and ventilator circuits). Series: DSB® Solo / DSB® Pro. Home use is a future extension.
Key In-hospital Advantages
- Suitable for mechanical ventilation: stays in the breathing circuit, no need to remove the flow sensor or adjust ventilator parameters; supports invasive/non-invasive/high-flow/tracheostomy.
- Near-silent: <35 dB at 0.3 m — ideal for neonatal, pediatric and night-time therapy.
- Low drug residue: <0.1 ml (per 3 ml dose) vs 0.8–1.2 ml for compressor nebulizers.
- Uniform particles: 0.5–10 μm (optimal 2.5–4.7 μm), reaching the lung target.
- No heat, no protein denaturation: preserves drug molecular structure, supporting biologics and gene therapy.
- No parameter adjustment: just 2 steps per treatment (add medication + switch).
Product Parameters
| Aerosolization rate (graded) | Low ≥0.1 / Medium ≥0.2 / High ≥0.25 mL/min |
| Medication cup capacity | 20 ml |
| Medication cup weight | 21 g |
| Battery life | ≥60 minutes |
| Vibration frequency | 110–130 kHz |
| Mesh | >3,000 precision conical orifices per mesh |
| Noise | <35 dB (0.3 m) |
Applicable Scenarios
Departments: ICU, NICU, pediatrics, respiratory and elderly care. Routes: invasive mechanical ventilation, non-invasive ventilator, high-flow nasal cannula, tracheostomy, and spontaneous breathing (mouthpiece/mask).
Clinical Backing
- Nebulized tobramycin: alveolar lining fluid concentration 250× higher than IV at 2.5 h.
- 90.9% Pseudomonas aeruginosa (PA) clearance at 28 days (Chest, 2022).
- Expert consensus on nebulization during mechanical ventilation recommends vibrating-mesh nebulizers (Grade E).
FAQ
1. How to nebulize safely during mechanical ventilation?
Keep the nebulizer in the breathing circuit; no need to remove the flow sensor or adjust ventilator parameters.
2. Which patients is it suitable for?
Spontaneously breathing patients and assisted-ventilation patients (invasive/non-invasive ventilator, high-flow nasal cannula, tracheostomy).
3. How much drug residue is left?
<0.1 ml (per 3 ml dose), lower than the 0.8–1.2 ml of compressor nebulizers.
4. Is it noisy?
<35 dB, nearly silent — suitable for neonatal, pediatric and night-time use.
5. Why vibrating mesh over compressor or ultrasonic?
Uniform particles, no heat denaturation, no extra gas source, no ventilator interference, and support for biologics and gene therapy.
DXneb™-Solo is a registered model (NMPA registration: Su-Xie-Zhu-Zhun 20262080132).
View the complete DXneb™ brand page.
China Mesh Nebulizer Manufacturer & Supplier
DSB Medical is a medical device manufacturer in Changzhou, China, supplying mesh nebulizers (piezoelectric vibrating mesh nebulizers) and medical inhalation devices with OEM / ODM / CDMO services. Scope includes device design, mold development, precision manufacturing, automated assembly, packaging and regulatory support.
Frequently Asked Questions
Q: Does DSB provide mesh nebulizer OEM / ODM / CDMO?
A: Yes. DSB provides device design, molding, precision manufacturing, automated assembly and regulatory support through its OEM / ODM / CDMO services.
Q: What settings are mesh nebulizers used for?
A: Mesh nebulizers are used in hospital, ICU, respiratory, pediatric and home care settings where inhaled medication delivery is required.
Q: Can DSB support clinical samples or BE studies?
A: For drug-device combination programs, DSB can support device prototypes, clinical sample supply and regulatory documentation. BE study support is provided according to the pharmaceutical company's study plan.
Structure and performance aligned with leading vibrating mesh nebulizers
DXneb™-Solo and DXneb™-Pro are medical vibrating mesh nebulizers built around the clinical design principles of leading international vibrating mesh platforms. They support aerosol drug delivery at every stage of a patient's respiratory journey: invasive mechanical ventilation, non-invasive ventilation (NIV), high-flow therapy (HF), tracheostomy and spontaneous breathing. The device can remain in the breathing circuit without repeatedly removing the flow sensor or adjusting ventilator parameters.
- Vibrating mesh aerosol delivery with uniform particle output, 0.5–10 μm in size and typically 2.5–4.7 μm for targeted lung deposition.
- More than 3,000 precision conical orifices per mesh, driven at high frequency to generate a stable fine mist.
- 20 ml medication cup capacity with less than 0.1 ml residual volume per 3 ml dose, supporting efficient drug utilization.
- Quiet operation below 35 dB at 0.3 m, suitable for neonatal, pediatric and overnight therapy.
- Battery-powered without an external gas source, with at least 60 minutes of operating time.
Self-developed algorithm: reducing leakage and mesh clogging risk
Leakage and mesh clogging are common clinical pain points in mesh nebulizers. DXneb™ uses a self-developed control algorithm to coordinate nebulization timing, mesh excitation and residual-liquid management, helping reduce leakage and mesh-clogging risk, improve continuous nebulization stability, and reduce post-use cleaning burden. This supports stable output during mechanical ventilation, high-flow oxygen therapy and extended continuous nebulization.
High-viscosity formulations and biologics
DXneb™ supports high-viscosity drug solutions and biologic therapies. Its non-heating, protein-sparing design helps reduce damage to drug molecular structure and preserve biological activity, supporting biologics, gene therapies and high-viscosity formulations that require precise aerosol delivery.
Full-journey compatibility
- Invasive mechanical ventilation: remains in the breathing circuit.
- Non-invasive ventilation: compatible with NIV circuits.
- High-flow therapy: supports simultaneous oxygen and nebulization.
- Tracheostomy: suitable for tracheostomy patients.
- Spontaneous breathing: mouthpiece and mask options for pediatric and adult patients.
Atomic-level smooth mesh pore walls
DXneb™ mesh pore walls are precision-finished to atomic-level smoothness, helping reduce residual medication accumulation and mesh clogging, while simplifying cleaning.
Mesh smoothness and biological activity
Atomic-level smooth mesh pore walls are an important precondition for preserving biologic activity. Insufficient internal smoothness can increase protein denaturation or inactivation as the formulation passes through the mesh. DXneb™ precision-finished pore walls help reduce protein denaturation risk and preserve biological activity.
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